منابع مشابه
Isolation of Mouse Salivary Gland Stem Cells
Mature salivary glands of both human and mouse origin comprise a minimum of five cell types, each of which facilitates the production and excretion of saliva into the oral cavity. Serous and mucous acinar cells are the protein and mucous producing factories of the gland respectively, and represent the origin of saliva production. Once synthesised, the various enzymatic and other proteinaceous c...
متن کاملA Review of Signet Ring cells in Salivary Gland Tumors
Objectives: Signet Ring Cells (SRCs) are often seen in gastrointestinal, breast, bile duct and lung invasive carcinomas. Observing these cells in benign and malignant lesions of the salivary glands is not common. Signet-ring cell adenocarcinoma is rare and is commonly seen in the secondary salivary glands. Although, the presence of SRCs in other neoplasms of the body is usually associated with ...
متن کاملALDH/CD44 identifies uniquely tumorigenic cancer stem cells in salivary gland mucoepidermoid carcinomas
A small sub-population of cells characterized by increased tumorigenic potential, ability to self-renew and to differentiate into cells that make up the tumor bulk, has been characterized in some (but not all) tumor types. These unique cells, namedcancer stem cells, are considered drivers of tumor progression in these tumors. The purpose of this work is to understand if cancer stem cells play a...
متن کاملMesenchymal Stem Cells Promote the Invasion in Salivary Gland Cancer on the Biomimetic Microsystem
As the participant of the tumor microenvironment, mesenchymal stem cells (MSCs) play an important role for further understanding the tumor progression, which gradually become the hotspot in tumor biology [1, 2]. In this work, we investigated the heterotypic interaction between MSCs and epithelial salivary gland cancer (ACC-M) in an in-vivo like tumor microenvironment by using a biomimetic micro...
متن کاملCancer stem cells: therapeutic targets
Cancer stem cells (CSCs) have been identified as rare cellular populations in many cancers, including leukemia and solid tumors. This minor subpopulation of cancerous cells is immortal tumor-initiating cells which thought to be responsible for cancer initiation, progression, metastasis, recurrence and drug/radiation resistance. Low proliferative rate, high self-renewing capacity, differentiatio...
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ژورنال
عنوان ژورنال: Oral Oncology
سال: 2013
ISSN: 1368-8375
DOI: 10.1016/j.oraloncology.2013.05.013